Dieting calcium supplements, magnesium, and you will phosphorus consumption and likelihood of heart attack into the Chinese grownups

Dieting calcium supplements, magnesium, and you will phosphorus consumption and likelihood of heart attack into the Chinese grownups

Controversial results have been reported about the association of calcium, magnesium, and phosphorus and stroke risk, but none in China. To investigate the association between dietary calcium, magnesium, phosphorus, and stroke incidence in Chinese adults, we collected data from the China Health and Nutrition Survey (CHNS) from 2004 to 2011, including 6411 participants aged 45–79 years and free of stroke at baseline. Diet was assessed by interviews combining 3-d 24-h food recalls and household food inventory weighing at each survey round. The stroke incident was identified based on the validated self-report. Multivariate Cox regression models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). For 32,024 person-years of follow-up, 179 stroke cases were documented. After adjustment for major lifestyle and dietary risk factors, calcium intake was positively associated with reduced stroke risk, and the HR of stroke comparing extreme quartiles was 0.53 (95% CI 0.29–0.96, Ppattern = 0.03). In further stratified analyses, significant heterogeneity across sex strata was found (Ptelecommunications = 0.03). Dietary calcium intake among men was more inversely related to stroke, with HRs being 0.33 (95% CI 0.15–0.76, P trend = 0.02), compared to 1.24 (95% CI 0.46–3.35, Ptrend = 0.89) among women. However, no significant association between stroke and magnesium or phosphorus was revealed. Our findings suggest that higher dietary calcium intake was associated with a lower risk of stroke in Chinese adults, particularly in men.


Given that an effective cerebrovascular state, coronary arrest is probably the leading reason behind demise for the created and you may developing places. A good ten% total yearly demise around the globe are estimated to-be attributable so you can they step one . Perhaps the heart attack survivors, just as much as fifteen–30% is actually forever handicapped 2 , which leads to just as much as 113 mil handicap-modified existence years shed step three . China provides the high estimated lifetime chance of coronary arrest worldwide (39.3%) depending on the 2016 in the world load out of disease (GBD) local studies cuatro . Apparently, coronary arrest might a life threatening social health issue to possess China when you look at the against the elevated ageing population. Hence, identifying the modifiable chance affairs is actually pressing toward cures and you may the advance off life quality of stroke clients together with protection out-of enormous socio-financial burden.

Losing weight calcium supplements, magnesium, and you will phosphorus consumption and you will likelihood of coronary attack during the Chinese adults

Whilst the perfect etiology is not completely elucidated, stroke could be thought a condition linked to hereditary and environmental risk factors (particularly weight reduction) or the interplay of them items. Extensive research shows that weightloss changes are advantageous to quit the new onset of coronary arrest 5,six,eight . A near relationships can be acquired ranging from calcium supplements, magnesium, phosphorus, and you can vascular safety, that are thought extremely important fitness ramifications to own vascular disease simply because they is control vascular calcification and endothelial description 8,9 . At this point, several research has checked out the relationship anywhere between this type of nutrition consumption and you will stroke risk ten,11,twelve , nevertheless the email address details are inconsistent. Instance, browse regarding Western european inhabitants demonstrated magnesium intake, not calcium was somewhat associated with a diminished risk of heart attack 11 . On the other hand, in america, calcium intake, in place of magnesium, results in ong males, magnesium intake is inversely of this heart attack twelve . Also, all these scientific studies was indeed used when you look at the west communities with a high consumption of those nutritional elements thirteen,14 . Although not, to our studies, little is well known concerning the relationship off dietary calcium, magnesium, and you will phosphorus intakes having heart attack chance in the Chinese society. The common losing weight consumption of those micronutrients certainly one of Chinese anyone drinking mostly plant-oriented dieting is actually considered below that of Europeans and you may Americans with a lot more dairy and you will meats circumstances fifteen . Within this perspective, a large-measure potential research in the Chinese people to supplement the newest association’s proof is actually undoubtedly called for. We, ergo, put research regarding the Asia Health and Nourishment Survey (CHNS) to check on the partnership ranging from slimming down calcium, magnesium, and you may phosphorus intakes and after that frequency of coronary attack within the Chinese people.

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